Python NotImplementedError is_kernel_driver_active on Raspberry Pi and some Linux systems

This issue is caused by PyUSB. It’s still in beta, but unfortunatelly there is no other alternative to easily access USB devices with Python. If you experience this issue, please follow this guide on how to resolve it by downgrading PyUSB pip module:

Edit: Please note that the 1.1.6 release of BlinkStick Package for Python fixes this issue.